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在囊性纤维化背景下,ENaC是宿主对细菌感染的易感性因素

Hamadoun Touré1,2, Nicolas Durand1, Mickael Orgeur3

  • 1Université Paris-Saclay, UVSQ, INSERM, U1173 Infection et Inflammation, Montigny-le-Bretonneux, France.

Communications biology
|April 24, 2025
PubMed
概括

在囊性纤维化 (CF) 模型中,表皮质通道 (ENaC) 的过活性增加了对Mycobacterium疹感染的易感性. 阻断ENaC可以恢复免疫反应并保护人免受感染.

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