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Updated: Nov 9, 2025

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从四代血统参考来看,人类的新突变率

David Porubsky1, Harriet Dashnow2,3, Thomas A Sasani2

  • 1Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA.

Nature
|April 24, 2025
PubMed
概括

本研究使用先进的测序技术对人类新突变 (DNM) 率进行了全面分析. 它揭示了基因组特征影响的突变率的显著变化以及生殖系突变的强烈父性偏差.

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