错误的血液分类和错误的输血是由于低滴度O组的整体血液复苏
Miriam Brown1, Deva Sharma1, Kaycie Atchison2
1Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Transfusion
|April 24, 2025
概括
低位数O组全血 (LTOWB) 输血可能导致创伤患者因样本污染而导致 ABO 类型错误. 这凸显了需要仔细的血液采样协议,以防止潜在的错误输血.
科学领域:
- 输血医学 输血医学
- 紧急医疗 紧急医疗
- 患者安全 患者安全
背景情况:
- 大规模出血复苏越来越多地使用低滴度组O全血 (LTOWB).
- 在服用LTOWB后,ABO误类型的潜在风险尚未得到充分探索.
- 这个案例系列调查了在创伤中使用LTOWB的ABO误类风险.
研究的目的:
- 为了突出LTOWB输血后ABO误编的风险.
- 识别 ABO 打字错误的潜在原因和后果.
- 为了强调血液采样协议的重要性.
主要方法:
- 对接受LTOWB的三个创伤病例的回顾性审查.
- 使用自动化列聚合技术进行 ABO 和 RhD 打字.
- 对不一致的打字结果进行调查,以确认真实血型.
主要成果:
- 在LTOWB错误地将患者识别为O组后的初始 ABO 类型化.
- 随访证实了所有病例的真血型为A组.
- 两名患者接受了ABO不兼容的血输血;没有报告严重的结果.
结论:
- 由于样本污染,LTOWB输血存在 ABO 排版错误的风险.
- 错误可能导致ABO不兼容的输血和潜在的溶血反应.
- 严格遵守采样协议,包括输血前的类型和对方抽取,至关重要.
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