在胃神经内分泌瘤中对内镜超声波进行系统审查:指导方针超过证据
Matteo Marasco1,2, Gianluca Esposito1,2,3, Marianna Signoretti1
1Digestive Disease Unit, Sant' Andrea University Hospital, ENETS Center of Excellence, Rome, Italy.
Clinical endoscopy
|April 24, 2025
概括
内镜超声波 (EUS) 对胃神经内分泌瘤 (g-NENs) 显示出希望,但需要更多证据. 需要进行更大规模的研究来确认其在治疗这些罕见瘤中的作用.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 胃神经内分泌瘤 (g-NENs) 的发病率正在上升,需要有效的诊断工具.
- 国际指导方针建议对g-NEN进行内镜超声波 (EUS),但证据有限.
研究的目的:
- 系统地审查有关EUS在g-NENs管理中的作用的现有文献.
- 评估EUS在评估内镜切除g-NEN的诊断效用和局限性.
主要方法:
- 在PubMed上按照PRISMA指南进行了全面的文献搜索.
- 包括回顾性和前性人类研究,重点关注g-NEN中的EUS.
主要成果:
- 只有七项研究,包括44个病例,符合纳入标准,这表明研究有限.
- EUS在评估瘤特征方面表现出潜力,但显示出可变的准确性,缺乏用于临床决策的强有力的证据.
- 欧盟瘤学有助于分期,但在神经内分泌瘤特异性研究中代表性不足.
结论:
- 关于EUS在g-NEN管理中的有效性和可靠性的知识差距很大.
- 更大的多中心研究和前性试验对于验证EUS的作用和完善g-NENs的临床指南至关重要.
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