在质子疗法中量化使用圆束计算机断层扫描:挑战和机遇
Hamid Ghaznavi1, Borna Maraghechi1,2, Hailei Zhang1
1Department of Radiation Oncology, WashU Medicine, St. Louis, MO 63110, United States of America.
Physics in medicine and biology
|April 24, 2025
概括
适应性辐射疗法 (ART) 使用每日成像来改善瘤向和储备健康组织. 本综述探讨了适应性质子疗法 (APT) 的圆束CT (CBCT),重点关注其应用,挑战和未来潜力.
科学领域:
- 医学物理 医学物理
- 辐射瘤学 辐射瘤学
背景情况:
- 放射治疗 (RT) 旨在最大限度地杀死瘤细胞,同时保护健康组织.
- 像自适应性RT (ART) 这样的先进技术对于减少不确定性边缘和改善正常组织节约至关重要.
- 质子疗法 (PT) 提供了诸如降低积分剂量和精确的远端剂量下降等优势,使其适合ART.
研究的目的:
- 审查形束计算断层扫描 (CBCT) 在质子疗法 (PT) 中的当前应用,以评估剂量和调整计划.
- 讨论使用CBCT用于自适应性质子疗法 (APT) 的进展,挑战和未来方向.
主要方法:
- 对CBCT在PT系统中的集成和应用的当前文献的综述.
- 分析CBCT在适应性治疗规划的日常成像中的作用.
- 在APT的背景下使用CBCT评估图像质量和剂量评估.
主要成果:
- 与适应性质子疗法 (APT) 的CT-on-rail (CToR) 相比,CBCT提供了与PT系统的潜在更简单的集成.
- 虽然CBCT图像质量通常比CToR差,但其对APT的可行性正在积极研究中.
- 在APT中利用CBCT进行剂量评估和计划调整方面取得了进展.
结论:
- 由于其更容易整合的潜力,CBCT是实现自适应性质子疗法 (APT) 的关键技术.
- 需要进一步的研究和开发,以克服与CBCT图像质量及其对APT剂量评估的影响有关的挑战.
- 为APT优化CBCT有望提高质子治疗中的治疗精度和患者结果.
关键词:
在CBCT中,CBCT是CBCT.蒙特卡罗的蒙特卡罗是一个非常好的城市.适应性辐射疗法适应性辐射疗法人工智能的人工智能是人工智能.计算机断层扫描 (CT) 是一种计算机断层扫描.质子疗法是一种质子疗法.更多相关视频
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