西班牙末期病患者感染性内心炎的结果:基于人口的研究
Daniel Gómez-Ramírez1, Carmen Olmos2,3, Cristina Fernández-Pérez4,5,6
1Instituto Cardiovascular, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), C/ Profesor Martín Lagos s/n, Madrid, 28040, Spain.
BMC infectious diseases
|April 24, 2025
概括
末期病 (ESRD) 患者面临更高的感染性内心炎 (IE) 风险和死亡率. 这项研究发现,患有IE的ESRD患者患有更多并发症和更少的手术,透析和手术对死亡率没有影响.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- 末期病 (ESRD) 的患者患有感染性内心炎 (IE) 的风险较高,结果较差.
- 在ESRD患者中,IE带来了独特的临床和微生物学挑战.
研究的目的:
- 分析西班牙ESRD的IE患者的临床特征和结果.
- 为了比较透析和非透析ESRD患者与IE之间的结果.
主要方法:
- 来自西班牙最低基本数据集的9,008个IE事件 (2016-2019) 的回顾性,基于人群的研究.
- 分析包括428名ESRD患者 (332名透析患者).
- 多变量和多级物流回归评估了与住院死亡率相关的因素.
主要成果:
- 患有IE的ESRD患者更年轻,患有更多的并发病,金色葡萄球菌和凝结酶阴性葡萄球菌感染率更高.
- 感染性休克在ESRD患者中更频繁 (12.1%与8.9%相比).
- 患有ESRD的患者接受心脏手术的频率较低 (12.6%对19.6%),住院死亡率较高 (33.4%对26.9%). 透析患者有更多的并发症和金黄色细菌感染.
结论:
- 患有ESRD的IE患者表现出不同的临床和微生物特征.
- 患有IE的ESRD患者接受心脏手术的可能性较低,并且在医院死亡率明显较高.
- 透析和心脏手术都不是ESRD患者IE死亡的独立预测因素.
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