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Updated: Jul 23, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
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空间成像解锁了绘制多发性骨髓瘤和外骨髓性疾病的潜力

Vanessa Desantis1, Alessandro Andriano1, Tim Düking2

  • 1Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), Section of Pharmacology, University of Bari Aldo Moro Medical School, Bari, Italy.

Journal of hematology & oncology
|April 24, 2025
PubMed
概括

多发性骨髓瘤 (MM) 中的外骨髓性疾病 (EMD) 显示出与骨髓疾病不同的特征. EMD表现出改变的BCL-2,EZH2和CD38表达,以及受损的T细胞免疫监测,表明新的治疗点.

关键词:
外骨髓性疾病是一种外骨髓性疾病.MACSimaTM成像系统的成像系统在 MICS 技术方面,多发性骨髓瘤是一种多发性骨髓瘤.

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Bone Disorders01:29

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...