住院期间神经系统的晚期改善是急性缺血性中风的预测因素
Huimin Zhao1, Qinrong Xu1, Peng Chen2
1Department of Neurology, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215000, Jiangsu, People's Republic of China.
European journal of medical research
|April 24, 2025
概括
在急性缺血性中风 (AIS) 患者中,晚期神经改善 (LNI) 预示着良好的预后,大约76%的人获得了良好的结果. 年龄较小,NIHSS得分较高和rt-PA治疗是LNI的关键预测因素.
科学领域:
- 神经学 神经学
- 脑卒中医学 脑卒中医学
- 临床预后 临床预后
背景情况:
- 急性缺血性中风 (AIS) 管理需要准确的预后指标.
- 早期神经改善 (ENI) 是一个已知的积极预后因素.
- 在AIS中晚期神经改善 (LNI) 的预后价值仍然不太了解.
研究的目的:
- 确定住院期间晚期神经改善 (LNI) 是急性缺血性中风 (AIS) 患者的有利预后指标.
- 确定与在AIS患者中实现LNI相关的预测因素.
主要方法:
- 来自两家埃及中风中心的中风治疗安全实施 (SITS) 登记册的回顾性分析.
- LNI定义为24小时内没有ENI,但在接受治疗后7天内有所改善.
- 多变量逻辑回归用于分析有利预后因素 (修改的兰金尺度0-2) 和LNI.
主要成果:
- 834名AIS患者中有130人 (15.6%) 呈现LNI,其中99人 (76.2%) 取得了良好的结果.
- ENI (OR=6.756) 和LNI (OR=5.760) 都独立地与良好的预后相关.
- 预测LNI的预测因素包括年轻年龄 (OR=0.973),更高的基线NIHSS得分 (OR=1.196),和rt-PA治疗 (OR=1.953).
结论:
- 晚期神经改善 (LNI) 是急性缺血性中风 (AIS) 中显著有利的预后指标.
- 大约四分之三的患有LNI的AIS患者取得了良好的结果.
- 年龄较小,基线NIHSS得分较高和rt-PA治疗是AIS患者LNI的显著预测因素.
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