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Updated: Jun 21, 2026

In situ Quantification of Pancreatic Beta-cell Mass in Mice
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在胰腺β细胞中的GLP-1R胆固醇结合部位的分子映射和功能验证

Affiong Ika Oqua1, Kin Chao2, Liliane El Eid1

  • 1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.

eLife
|April 24, 2025
PubMed
概括

高胆固醇饮食在体内会损害类似葡萄糖-1受体 (GLP-1R) 的功能. 降低胆固醇合成改善GLP-1R活性,特定受体突变增强胰岛素分泌,提供新的治疗点.

关键词:
这是一个GLP-1RR.模拟MDMD的模拟细胞生物学 细胞生物学胆固醇 胆固醇 胆固醇 是一种不同的形物是不一样的.小小的岛屿小小的岛屿这里是鼠标鼠标鼠标鼠标鼠标鼠标.2 型糖尿病 2 型糖尿病

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