,.

Ashley R Brown1,2, Grant A Fox1,2, Irene M Kaplow1,2,3

  • 1Ray and Stephanie Lane Department of Computational Biology, Carnegie Mellon University, Pittsburgh, PA, United States.

Frontiers in genetics
|April 24, 2025
PubMed
概括

系统性MPRA (sysMPRA) 能够在多种组织中对基因增强剂进行高效的体内分析. 这种方法克服了动物研究中的挑战,揭示了遗传变异和转录因子结合部位的调节效应.

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