相关实验视频
Updated: May 10, 2025

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急性肠道穿孔 在患有连接组织疾病的患者中进行肠道后准备
Omar Brijawi1, Spencer Jude1, Evan Hartman2
1Department of Internal Medicine, Mount Carmel Health System, Grove City, USA.
European journal of case reports in internal medicine
|April 24, 2025
概括
用口服异体剂进行肠道制备可能会导致罕见但严重的并发症,如穿孔,特别是在有结缔组织疾病的患者中. 这一案例凸显了与这些常见药物相关的潜在风险.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 内部医学 内部医学
背景情况:
- 异位性口服药物是肠道准备的标准,因为它们具有有利的副作用.
- 肠道穿孔是一种罕见但严重的并发症,与肠道准备有关.
- 结缔组织疾病和某些药物 (NSAID,类固醇) 可以损害结肠完整性,增加穿孔风险.
研究的目的:
- 在患有结缔组织疾病的患者中,在口服异位体肠道制备后报告肠道穿孔的致命病例.
- 强调常用的肠道制备剂在脆弱患者群体中的潜在风险.
主要方法:
- 案例报告的呈现方式.
- 审查患者的临床病史,成像和治疗过程.
- 讨论风险因素,包括结合组织疾病和药物使用.
主要成果:
- 一名67岁的男性患有不分化的混合结合组织疾病,在接受口服异位体肠道制剂后经历了肠道穿孔.
- 图像检查证实了结肠穿孔.
- 尽管进行了积极的医疗和手术管理,但患者因并发症而死亡.
结论:
- 口服异体性肠道制备剂并非没有风险.
- 患有结缔组织疾病的患者在接受口服异位体剂的肠道制备时,患有包括穿孔在内的不良事件的风险较高.
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