与口腔癌相关的危险因素:印度泰兰加纳州的一项基于医院的病例控制研究
Monica Mocherla1,2, Pushpanjali Krishnappa2, Denny John3
1Department of Public Health Dentistry, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India.
Contemporary clinical dentistry
|April 24, 2025
概括
长期使用烟草,无论是吸烟还是无烟,都会显著增加口腔癌的风险. 在这项研究中,慢性口腔创伤也成为了显著的危险因素.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 口腔癌是全球重要的健康问题.
- 烟草使用和酒精消费是已知的风险因素,但其他因素的影响仍在争论中.
- 了解口腔癌的多因素性质对于有效的预防策略至关重要.
研究的目的:
- 调查各种风险因素与口腔癌发病率之间的关联.
- 量化归因于特定因素的风险,如烟草使用时间和慢性口腔创伤.
- 应用倾向性评分方法来进行可靠的风险因素分析.
主要方法:
- 在印度海德拉巴进行了一项病例控制研究,涉及238例口腔癌病例和450例对照.
- 关于风险因素的数据是通过使用结构化问卷进行直接采访来收集的.
- 倾向得分方法和加权后勤回归被用于分析关联.
主要成果:
- 在病例和对照之间,在烟草使用,酒精消费和蔬菜摄入量方面观察到显著差异.
- 长期使用烟草 (超过10年) 显示,无烟烟草 (OR=9.09) 和吸烟 (OR=8.96) 的几率比率显著增加.
- 每日饮酒量 (OR=5.69) 和慢性口腔创伤 (OR=3.00) 也被确定为口腔癌的重要危险因素.
结论:
- 这项研究强化了烟草的使用,特别是它的持续时间,作为口腔癌的主要风险因素.
- 证据支持慢性口腔创伤的作用是导致口腔癌发展的因素.
- 这些发现强调了针对戒烟和口腔健康的有针对性的干预措施的重要性.
更多相关视频
04:45Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
Published on: May 10, 2021
3.6K
07:43Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples
Published on: July 29, 2017
9.6K
相关概念视频
Cancer Prevention
6.0K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.0K
Skin Cancer
2.9K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
2.9K
mTOR Signaling and Cancer Progression
3.6K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
The mTOR pathway or the...
3.6K
Tooth Anatomy
269
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
269
Cancer Survival Analysis
298
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
298
Replicative Cell Senescence
3.6K
Replicative cell senescence is a property of cells that allows them to divide a finite number of times throughout the organism's lifespan while preventing excessive proliferation. Replicative senescence is associated with the gradual loss of the telomere — short, repetitive DNA sequences found at the end of the chromosomes. Telomeres are bound by a group of proteins to form a protective cap on the ends of chromosomes. Embryonic stem cells express telomerase — an enzyme that adds...
3.6K
