红细胞分布宽度-白蛋白比率与心血管疾病之间的关联
Yan Liu1, Shougang Sun2, Ling Liu3
1The Second Clinical Medical School, The Second Hospital of Lanzhou University, Lanzhou, China.
红细胞分布宽度与白蛋白比率 (RAR) 与心血管疾病 (CVD) 风险和死亡率的增加有关. 较高的RAR水平与更大的风险相关,这表明RAR是潜在的独立心血管疾病风险因素.
科学领域:
- 生物医学研究的研究.
- 临床诊断 临床诊断 临床诊断
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 是全球主要的死亡原因.
- 红细胞分布宽度 (RDW) 和白蛋白 (ALB) 具有临床相关性.
- RDW与ALB (RAR) 的比率可能为心血管疾病提供诊断优势.
研究的目的:
- 在一般人群中调查RAR和心血管疾病之间的关联.
- 探索RAR与心血管和全因死亡率之间的关系.
- 评估RAR作为心血管疾病的独立风险因素的潜力.
主要方法:
- 对12765名参与者的分析.
- 使用了后勤和考克斯回归模型.
- 使用了受限制的立方线,调解分析和ROC曲线.
主要成果:
- RAR与心血管疾病正相关.
- RAR显示了非线性,与所有原因和心血管死亡率的积极关联.
- 对心血管死亡率而言,RAR的区分能力强于对所有原因死亡率的区分能力.
结论:
- 罕见AR显著与心血管疾病风险增加有关.
- 较高的RAR水平与死亡率的增加有关.
- 罕见ARAR可以作为心血管疾病的独立风险因素,有助于其管理.
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