认知障碍与地中海饮食和死亡率的相关性:一个前性队列研究
Ling Li1, Xiaoxiao Zheng1, Hongyue Ma1
1Department of Neurology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Frontiers in aging neuroscience
|April 24, 2025
概括
坚持地中海饮食和认知障碍相互作用,影响心血管死亡率. 更严格地遵守地中海饮食可能会降低心血管风险,特别是在认知障碍患者中.
科学领域:
- 营养科学 营养科学
- 流行病学 流行病学
- 老年学是一门学科.
背景情况:
- 长期遵守地中海饮食与改善认知功能有关.
- 关于遵守地中海饮食和认知障碍对长期死亡率的综合影响的证据有限.
研究的目的:
- 研究地中海饮食的坚持和认知障碍对长期死亡结果的相互作用.
- 评估这些因素对所有原因和心血管死亡率的影响.
主要方法:
- 利用了2520名参与国家健康和营养检查调查 (NHANES) (2011-2014) 的数据.
- 通过使用替代地中海饮食指数 (aMED) 评估地中海饮食的坚持,并通过CERAD,AFT和DSST评估认知功能.
- 将NHANES数据与国家死亡指数 (NDI) 连接起来,用于截至2019年12月的死亡结果,采用Cox比例危险回归模型.
主要成果:
- 较高的aMED分数与降低全因和心血管死亡风险相关.
- 认知障碍与所有原因和心血管死亡风险的增加有关.
- 在较低的aMED分数和认知障碍之间发现了相互作用,增加了与心血管相关的死亡率 (p=0.028).
结论:
- 地中海饮食的坚持和对心血管死亡率的认知障碍之间存在相互作用.
- 遵守地中海饮食显著影响心血管死亡率,特别是在认知障碍患者中.
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