饮食中较高的维生素D摄入量会影响美国老年人的大脑和精神功能:一个横截面分析
Huizhen Chen1, Xing Pang2, Yinhui Huang2
1Department of Laboratory, Jinjiang Municipal Hospital, Quanzhou, China.
Frontiers in nutrition
|April 24, 2025
概括
更高的饮食维生素D摄入量与更好的认知功能和老年人抑郁症的减少有关. 这项研究强调了维生素D对老年人大脑健康的重要性.
科学领域:
- 老年学是一门学科.
- 营养神经科学 营养神经科学
- 公共卫生 公共卫生
背景情况:
- 维生素D在维持认知功能和心理健康方面起着至关重要的作用.
- 新出现的证据表明,在老年人群中,维生素D水平与神经健康之间存在联系.
研究的目的:
- 研究美国老年人饮食维生素D摄入量与认知表现之间的关联.
- 为了检查饮食维生素D摄入量与老年人抑郁症状之间的关系.
主要方法:
- 分析了2013-2014年国家健康和营养检查调查 (NHANES) 的数据.
- 包括1344名老年参与者,按饮食维生素D摄入量 (D2+D3) 分类.
- 认知功能通过CERAD,DSST和Animal Fluency测试进行评估;抑郁症通过PHQ-9进行评估,并对混因素进行调整.
主要成果:
- 较高的维生素D摄入量 (第三三位数,≥4.9mcg/day) 与CERAD (OR:0.77) 和动物流利性测试 (OR:0.63) 中表现不佳的几率显著降低有关.
- 维生素D摄入量最高的第三级老年人也显示出抑郁症的几率较低 (PHQ-9分数>4) (OR:0.68).
- 在调整年龄,性别,种族,教育,体力活动和饮食因素后,统计学意义保持不变.
结论:
- 饮食维生素D摄入量与改善认知功能和减少老年人的抑郁症状有关.
- 研究结果表明,维生素D可能是增强老年人认知健康和心理健康的可修改因素.
- 建议进行进一步的纵向研究,以确认因果关系并阐明潜在的生物机制.
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