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All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
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Correction: A man in his twenties with fever and severe abdominal pain below the right costal margin.

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由颗粒细胞殖民地刺激因子引发的风炎.

Andreas Gaustad1, Marthe Halsan Liff2, Aleksander Nordberg Nørgaard3

  • 1Medisinsk avdeling, Diakonhjemmet sykehus, Oslo.

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke
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颗粒细胞殖民地刺激因子 (G-CSF) 在淋巴瘤患者中可引起大关节炎,呈发烧和CRP升高的形式. 停止G-CSF和使用成像是诊断和治疗的关键.

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科学领域:

  • 在瘤学瘤学.
  • 血管医学 血管医学
  • 药理学 药理学是指药理学的学科.

背景情况:

  • 一名60岁的男性被诊断出患有扩散性大B细胞淋巴瘤.
  • 患者在用G-CSF进行化学治疗后出现发烧,肌痛和昏迷.

研究的目的:

  • 报告一种罕见的G-CSF诱导的风炎病例.
  • 为了突出发烧后G-CSF治疗的诊断考虑.

主要方法:

  • 临床病例的介绍.
  • 实验室调查,包括对C反应蛋白 (CRP) 的监测.
  • 计算机断层扫描 (CT) 扫描用于成像.

主要成果:

  • 尽管接受了抗生素治疗,但患者发烧和CRP升高.
  • 脑电图扫描显示出主动脉炎,怀疑是G-CSF诱导的.
  • 停止使用G-CSF并开始服用普雷迪尼索隆导致了快速改善.

结论:

  • 由G-CSF引起的风炎是患有发烧后G-CSF治疗对抗生素无反应的患者的潜在诊断.
  • 先进的成像对于诊断至关重要.
  • 迅速停止G-CSF是主要的管理策略.