在使用布鲁赫的膜开口区域的儿童中,大光盘的新值
Julia V Stingl1, Cordula Braun1, Sara Walter1
1Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany.
Translational vision science & technology
|April 24, 2025
概括
儿科大光盘 (LOD-C) 显示出比正常大小的儿科光盘 (NOD-C) 更厚的外皮皮质视网膜神经纤维层 (pRNFL) 厚度. 光盘大小显著影响儿童的RNFL和BMO-MRW测量,需要仔细解释.
科学领域:
- 眼科医生 眼科 眼科
- 儿科眼科医生 儿科眼科医生
- 玻璃眼研究研究 玻璃眼研究
背景情况:
- 光盘的尺寸可以影响对围状视网膜神经纤维层 (pRNFL) 和布鲁赫膜开口最小边缘宽度 (BMO-MRW) 的测量.
- 了解这些影响对于准确的青光眼诊断至关重要,特别是在儿科患者中.
研究的目的:
- 为了比较大光盘 (LOD-C) 的儿童与正常尺寸光盘 (NOD-C) 的儿童和大光盘 (LOD-A) 的成年人之间的pRNFL厚度.
主要方法:
- 每组包括127只眼睛 (n=381).
- 通过布鲁赫膜开口 (BMO) 面积定义的大光盘≥2.5 mm2.
- 在儿科和成人大光盘组之间比较pRNFL厚度和BMO-MRW.
主要成果:
- 全球pRNFL的平均厚度在LOD-C (100.2±12.1μm) 中明显比NOD-C (95.9±11.7μm) 厚.
- 与NOD-C (320.7 ± 10.5 μm) 和LOD-A (252.9 ± 45.8 μm) 相比,全球BMO-MRW平均值在LOD-C (280.0 ± 41.1 μm) 中显著较薄.
- 在pRNFL和BMO面积之间发现了正相关性,在BMO-MRW和BMO面积之间发现了负相关性,在特定的BMO面积门上发现了更强的关联.
结论:
- 在BMO面积<1.9mm2和>2.8mm2的儿科光盘中,RNFL和BMO-MRW需要谨慎解释,因为光盘大小对光盘大小有很大的影响.
- 儿科大光盘的新门可以帮助计算RNFL和MRW上的磁盘大小影响,改善儿童的青光眼诊断.
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