人体前额皮层中的刺激表现支持工作记忆中的灵活控制
Zhujun Shao1,2, Mengya Zhang1, Qing Yu1
1Institute of Neuroscience, State Key Laboratory of Brain Cognition and Brain-inspired Intelligence Technology, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.
eLife
|April 24, 2025
概括
额叶皮层刺激表示支持灵活的工作记忆 (WM) 控制,而视觉皮层表示有助于精确的维护. 这种神经编码方案适应不断变化的环境.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
背景情况:
- 工作记忆 (WM) 涉及暂时存储和操作视觉信息.
- 在WM过程中神经表示分布在视觉和额叶皮层.
- 额叶和视觉皮层在WM刺激表现中的确切作用仍在争论中.
研究的目的:
- 探讨前额叶皮层刺激表现在WM中促进灵活的控制需求的假设.
- 区分前额和视觉皮层在WM维护与控制中的作用.
主要方法:
- 功能磁共振成像 (fMRI) 用于测量大脑活动.
- 参与者在简单的WM维护和复杂的基于规则的分类之间进行灵活切换.
- 多模块循环神经网络用于计算建模.
主要成果:
- 额叶皮层显示了增强的刺激表现跟踪WM控制需求.
- 视觉皮层显示了增强的刺激表现,跟踪精确的WM维护需求.
- 不同的正面表示与基于控制需求的类别表示进行了交易.
结论:
- 这些发现使关于WM神经表征的辩论协调起来.
- 经验和计算证据支持WM控制的灵活的正面刺激表示.
- 这种神经编码方案适应了动态的环境需求.
相关概念视频
Somatosensory, Motor, and Association Cortex
300
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
300
Role of Cerebellum and Prefrontal Cortex in Memory
206
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
206
Association Areas of the Cortex
4.5K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
4.5K
Working Memory
84
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
84
Motor and Sensory Areas of the Cortex
2.5K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor...
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor...
2.5K
Lobes of the Cerebrum
429
The cerebral cortex, a critical structure of the brain, is intricately divided into two hemispheres, each consisting of four distinct lobes: occipital, temporal, frontal, and parietal. These lobes function cooperatively to regulate various cognitive and sensory functions, forming the basis of our complex neural capabilities.
Frontal lobe
The frontal lobes, located behind the forehead, are the command center of our brain, controlling personality, intelligence, and voluntary muscle movements....
Frontal lobe
The frontal lobes, located behind the forehead, are the command center of our brain, controlling personality, intelligence, and voluntary muscle movements....
429


