透视甲状腺切除术后的生活质量与传统的开放甲状腺切除术后的生活质量:系统性审查和元分析
Vishesh Agrawal1, Sanjay Kumar Yadav2, Pawan Agarwal3
1AIIMS, Nagpur, India.
Langenbeck's archives of surgery
|April 24, 2025
概括
在内镜甲状腺切除术 (ETx) 和开放甲状腺切除术 (OTx) 后的生活质量 (QoL) 似乎相似. 这次元分析发现,这两种手术方法在 QoL 结果,疼痛或满意度方面没有显著差异.
科学领域:
- 手术瘤学手术瘤学
- 生活质量研究 研究 生命质量研究
- 进行元分析分析.
背景情况:
- 评估与健康相关的生活质量 (QoL) 对于评估外科手术结果至关重要.
- 内镜甲状腺切除术 (ETx) 为传统的开放甲状腺切除术 (OTx) 提供了一种最小侵入性的替代方案.
- 在以患者为中心的决策中,ETx和OTx之间的比较QoL数据是必不可少的.
研究的目的:
- 系统地评估和比较与健康相关的生活质量 (QoL) 结果后内镜甲状腺切除术 (ETx) 与开放甲状腺切除术 (OTx).
- 综合当前关于QoL,疼痛和ETx后患者满意度的证据,与OTx相比.
主要方法:
- 对比ETx和OTx后的QoL结果的研究进行了元分析.
- 在PubMed,EMBASE和Cochrane图书馆进行文献搜索.
- 使用ROBINS-I工具评估偏差风险;主要总结措施是平均差异 (MD).
主要成果:
- 包括三项研究:两项比较跨口ETx与OTx,一项比较TransaxillaryETx与OTx.
- 使用SF-36尺度,在ETx和OTx之间的QoL结果中没有发现显著差异.
- 疼痛评分 (视觉模拟尺度) 和整体患者满意度在两个手术方法之间是可比的.
结论:
- 目前的证据表明,内镜甲状腺切除术 (ETx) 和开放甲状腺切除术 (OTx) 之间的QoL结果相似.
- 现有研究中的异质性和有限的样本大小限制了概括性.
- 需要使用经过验证的 QoL 仪器 (例如,ThyPRO-39) 进行高质量,大规模的随机对照试验.
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