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Updated: Aug 3, 2026

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
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面膜上超分子组件作为生物直角门为梅尔法兰

Hanlin Xu1, Qingxin Yao1, Xiaoqian Hu1

  • 1State Key Laboratory of Chemical Resource Engineering, MOE Key Lab of Biomedical Materials of Natural Macromolecules, Beijing University of Chemical Technology, Beijing, 100029, China.

Angewandte Chemie (International ed. in English)
|April 24, 2025
PubMed
概括

这项研究引入了一种细胞选择性的生物对等前药物策略,以改善共价药物向. 新的设计增强了癌细胞的选择性,减少了对正常组织的毒性,并改善了治疗结果.

关键词:
生物对等的前药物.癌症 癌症 癌症 癌症同价药物药物是共价药物.酶指导的超分子组合.膜传送器 膜传送器

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Assembly of Signaling Complexes01:30

Assembly of Signaling Complexes

Multiprotein signaling complexes are formed in a dynamic process involving protein-protein interactions at the cytoplasmic domain of transmembrane receptors or enzymatic and non-enzymatic proteins associated with the receptor. These complexes ensure the activation and propagation of intracellular signals that regulate cell functions.
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...