Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

37
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
37
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

66
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
66
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

106
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
106

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Genome sequence of a divergent strain of canine distemper virus detected in New Zealand fur seals.

Microbiology resource announcements·2025
Same author

High pathogenicity avian influenza (HPAI) H5N1 virus detected in brown Skua using portable laboratory while at sea in Antarctica.

Microbiology resource announcements·2025
Same author

The perspectives of autistic adolescents and their parents on sleep strategies for insomnia.

Sleep medicine·2025
Same author

Identifying core leadership competencies to success non-communicable disease control and prevention programs: A mixed-methods study.

PloS one·2025
Same author

Addressing health service equity through telehealth: A systematic review of reviews.

Digital health·2025
Same author

Effectiveness of Quality Use of Medicines (QUM) Programs and Strategies in Saudi Arabia: A Narrative Review.

Drug, healthcare and patient safety·2025

相关实验视频

Updated: May 10, 2025

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

14.8K

阿尔法-1生物标志物联盟研究的理由和设计

Monica P Goldklang1, Cheryl Pirozzi2, Igor Barjaktarevic3

  • 1Columbia University, New York, New York, United States.

Chronic obstructive pulmonary diseases (Miami, Fla.)
|April 24, 2025
PubMed
概括

阿尔法-1抗素缺乏症 (AATD) 会导致COPD,并带来各种症状. 这项研究使用CT扫描和生物标志物来了解AATD.

关键词:
阿尔法-1抗素缺乏症生物标志物 生物标志物计算机断层扫描 (CT) 是一种计算机断层扫描.突发性质炎症是什么意思螺旋测量是一种螺旋测量.

更多相关视频

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

36.2K
A Cross-Disciplinary and Multi-Modal Experimental Design for Studying Near-Real-Time Authentic Examination Experiences
00:08

A Cross-Disciplinary and Multi-Modal Experimental Design for Studying Near-Real-Time Authentic Examination Experiences

Published on: September 4, 2019

6.9K

相关实验视频

Last Updated: May 10, 2025

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

14.8K
Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

36.2K
A Cross-Disciplinary and Multi-Modal Experimental Design for Studying Near-Real-Time Authentic Examination Experiences
00:08

A Cross-Disciplinary and Multi-Modal Experimental Design for Studying Near-Real-Time Authentic Examination Experiences

Published on: September 4, 2019

6.9K

科学领域:

  • 肺部医学 肺部医学
  • 遗传学 遗传学 是一个
  • 生物标志物研究 生物标志物研究

背景情况:

  • 阿尔法-1抗素缺乏症 (AATD) 是慢性阻塞性肺病 (COPD) 的主要遗传驱动因素.
  • 在患有AATD的个体中,临床表现和疾病进展存在显著的变异性,尽管有共同的遗传变异.
  • 了解这种异质性对于个性化管理策略至关重要.

研究的目的:

  • 研究计算机断层扫描 (CT) 成像和血清/呼吸道生物标志物如何解释AATD中的表型变异性.
  • 确定与AATD患者的疾病严重程度和进展相关的因素.
  • 建立一个全面的纵向队列,用于AATD的深度表型.

主要方法:

  • 在3年内对270名成人PiZZ AATD参与者进行了多中心纵向研究.
  • 数据收集包括螺旋测量,患者报告的结果,生物采样 (血液,唾液,鼻膜) 和胸部CT成像.
  • 将进行基因分析 (SERPINA1测序) 和从PBMCs生成iPSC.

主要成果:

  • 通过横截面和纵向成像,生理学和症状学数据对AATD队列进行深度表征.
  • 从CT成像中获得的定量肺瘤测量和新的气道改造指标.
  • 爱尔兰的一个验证队列将独立地使用相同的程序注册患者.

结论:

  • 这项研究代表了第一个AATD队列,整合了详细的定量肺气测量和先进的成像.
  • 这些发现旨在阐明AATD异质性的潜在机制.
  • 确定影响AATD疾病严重程度和进展的关键因素.