功能性光膜成像探头测量在临床上相关的食管胃结口出口阻塞中的肺后扩张
James D Miller1, Zachary L Mitchell1, Abigail L Ellington1
1Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Neurogastroenterology and motility
|April 24, 2025
概括
肺部扩张 (PD) 有效地治疗了缩小的食道开口,改善了张力和患者的症状. 治疗后的测量没有预测需要重复延迟.
科学领域:
- 胃肠病学 胃肠病学
- 食道生理学 食道生理学
- 干预性内镜检查是干预性的内镜检查.
背景情况:
- 肺部扩张 (PD) 是减少食道开口的标准治疗方法.
- 功能性光阻平面测量 (FLIP) 评估了下食道 (LES) 的生理学.
- 这项研究评估了PD后的FLIP测量和食道开口分类.
研究的目的:
- 评估PD后FLIP测量和食道开口分类的变化.
- 确定这些变化是否与症状改善相关.
- 为了确定PD后的FLIP测量是否预测需要重复扩张.
主要方法:
- 对患有食管胃结出口阻塞 (EGJOO) 的患者进行了回顾性分析,这些患者正在接受PD.
- FLIP,定时食道图 (TBE) 和测力仪被用于诊断.
- 在同一个内镜检查期间,进行了PD后的FLIP测量.
主要成果:
- PD显著增加了平均延展性指数 (DI) 和直径 (p < 0.001).
- 平均Eckardt分数在PD后显著改善 (6.25至1.2).
- 扩张后的DI,直径和食道开口模式在需要重复扩张的患者和不需要重复扩张的患者之间没有区别.
结论:
- PD有效地改善食道开口和患者的症状 (埃卡德得分).
- 后PD FLIP测量 (DI,直径) 和打开模式不能可靠地预测需要重复扩张的需要.
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