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Updated: May 10, 2025

Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
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Detection of Alternative Splicing During Epithelial-Mesenchymal Transition

Published on: October 9, 2014

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在剪接因子突变白血病中,错误剪接衍生的新抗原和相关的TCR

Won Jun Kim1, Edie I Crosse2, Emma De Neef3

  • 1Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA.

Cell
|April 24, 2025
PubMed
概括

癌症突变会产生异常的RNA信息, 研究人员发现这些新抗原可以训练T细胞抗击白血病,

关键词:
核糖核酸拼接SF3B1 其他其他:T细胞受体U2AF1 其他在 ZRSR2急性骨髓性白血病免疫疗法骨髓发育不良综合征新抗原

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