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Updated: Jun 14, 2025

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癌症中的乳酸:专注于机制和转化医学

Zhengyu Hu¹, Wenchao Li¹, Lingyu Wei²

¹Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, China; Cancer Research Institute, School of Basic Medicine Sciences, Xiangya School of Medicine, Central South University, Changsha, China; Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, NHC Key Laboratory of Carcinogenesis, Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Hunan Key Laboratory of Cancer Metabolism, Changsha, China.

Biochimica et biophysica acta. Reviews on cancer

|April 24, 2025

概括

铁结合型糖蛋白 - - 乳酸,通过抑制瘤生长和扩散,表现出抗癌性质. 它的安全性概况表明它有可能作为癌症生物标志物和治疗剂.

科学领域:

生物化学生物化学
免疫学免疫学免疫学
在瘤学瘤学.

背景情况:

乳酸是一种结合铁的糖蛋白,具有多种生物功能.
已知的作用包括抗菌,抗病毒,抗炎和免疫调节活动.
新兴研究强调了乳酸对瘤发生和瘤微环境的影响.

研究的目的:

总结一下乳酸铁素对抗癌症的分子机制.
探索乳酸与各种癌症进展的关联.
突出其在癌症治疗中的临床潜力.

主要方法:

对现有的关于乳酸铁素生物特性文献的综述.
对详细说明乳酸对瘤扩散,入侵和转移的影响的研究分析.
检查关于乳酸铁素作为生物标志物和药物输送系统的作用的研究.

主要成果:

乳酸通过多个途径抑制瘤的扩散,入侵和转移.
有证据表明,乳酸与各种癌症的恶性进展有关.
乳酸显示出作为癌症生物标志物和药物载体的潜力.

结论:

乳酸具有显著的抗癌作用.
它的安全性支持其在癌症治疗中的应用.
乳酸是增强抗癌疗法的有希望的候选者.

关键词:

生物标志物生物标志物癌症癌症癌症癌症癌症治疗治疗癌症治疗药物输送是药物输送的过程.铁的代谢铁的代谢乳酸铁素是乳酸铁素的一种.瘤微环境是一个微环境.

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