使用自动化决策支持工具来改善HIV处方:可行性研究
Aidan T Ireland1, Jennifer Ward2, Heather Dolby3
1MRCP, South Tees NHS Foundation Trust, Middlesbrough, UK.
HIV medicine
|April 24, 2025
概括
一个新的决策支持工具 (DST) 显示出对优化抗逆转录病毒疗法 (ART) 处方的希望. 这种工具可以提高HIV治疗的成本效益和患者和临床医生的共同决策.
科学领域:
- 传染性疾病 传染性疾病
- 药物经济学 药物经济学
- 医疗信息学 医疗信息学
背景情况:
- 对艾滋病毒感染者 (PLWH) 进行抗逆转录病毒治疗 (ART) 的选择是复杂的,受个人因素和临床医生的判断的影响.
- 英国艾滋病毒协会 (BHIVA) 促进成本效益高的处方和共享决策.
- 评估用于优化ART治疗方案的新工具对于患者护理和资源管理至关重要.
研究的目的:
- 评估ART处方的原型自动化决策支持工具 (DST) 的可接受性和潜在影响.
- 提高ART治疗方案的安全性,个性化和成本效益.
- 将处方实践与BHIVA指导方针和患者偏好保持一致.
主要方法:
- 一项对PLWH和临床医生的调查评估了治疗偏好和DST接受度.
- 开发了一个DST来解释电子患者记录数据与2022年BHIVA针对ART转换选项的指导方针.
- DST被应用于接受ART的患者队列,并计算了潜在的成本节约.
主要成果:
- 86.7%的PLWH受访者愿意转向更具成本效益的ART.
- 虽然大多数临床医生优先考虑低成本治疗,但对ART成本的认识很低 (38%).
- 对于符合条件的患者来说,发现了潜在的每月成本节省28.4% (26,630.25英).
结论:
- 使用BHIVA建议和常规数据的DST可能是患者和临床医生可以接受的.
- DST有可能在ART处方中实现显著的成本节约.
- 相当数量的PLWH愿意考虑为成本效益而进行ART更改.
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