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Updated: May 20, 2025

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
10:21

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

Published on: February 21, 2018

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在多发性骨髓瘤中,USP5通过激活STAT2-PFKFB4介导的糖解来激发免疫抑制的微环境

Shifeng Long1, Ting Ding2, Yongliang Zheng2

  • 1Department of Hematology, The Affiliated Hospital of Jinggangshan University, Ji'an, 343000, Jiangxi Province, People's Republic of China. longshifeng1910@163.com.

Cancer immunology, immunotherapy : CII
|April 24, 2025
PubMed
概括

乌比基特异性蛋白酶5 (USP5) 促进多发性骨髓瘤细胞生存和糖解,导致乳酸生产和免疫抑制. 抑制USP5可能为多发性骨髓瘤提供一种新的治疗策略.

关键词:
葡萄糖溶解是什么? 葡萄糖溶解巨细胞的两极分化多发性骨髓瘤是一种多发性骨髓瘤.USP5 美国

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