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Updated: May 10, 2025

Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities
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Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities

Published on: October 2, 2018

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萨克西托克辛同源结合和被安兰萨克西菲林斯中和的结构基础

Sandra Zakrzewska1, Samantha A Nixon1, Zhou Chen1,2

  • 1Cardiovascular Research Institute, University of California, San Francisco, CA, USA.

Nature communications
|April 24, 2025
PubMed
概括

萨克西菲林 (Sxphs) 作为毒素海绵,结合萨克西托克辛 (STX) 和其变体. 这些蛋白质逆转STX诱导的通道 (NaV) 阻塞,有助于毒素检测和缓解策略.

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