跑步机在患有MASLD的老年人心脏代谢风险因素和肝功能标志物上的效果:一项随机对照试验
Jiyoun Kim1, Sungju Lee2, Yong-Seok Jee3,4
1Department of Exercise Rehabilitation, Gachon University, Hombakmoero, Yeonsu-gu, Incheon, 406-799, Korea.
BMC sports science, medicine & rehabilitation
|April 24, 2025
概括
一个为期12周的步行计划显著改善了代谢综合征和MASLD的老年人身体组成,心脏代谢健康和肝功能. 这种干预措施增强了身体活动,并减少了关键的健康风险因素.
科学领域:
- 老年学是指老年学的学科.
- 运动生理学 运动生理学
- 肝病学 肝病学是一种肝病学.
背景情况:
- 经常步行显示出改善代谢相关脂肪性肝病 (MASLD) 的潜力.
- 有限的研究存在于步行干预措施对代谢综合征和MASLD的老年人的影响.
研究的目的:
- 为了研究12周步行干预对代谢综合征风险因素的影响.
- 评估代谢综合征和MASLD的老年人肝功能指标和超声检测结果的变化.
主要方法:
- 66名患有代谢综合征和MASLD的参与者 (65-85岁) 被分为对照组和步行计划组.
- 步行组 (WPG) 进行30分钟的低到中等强度步行,每周6天,持续12周.
- 运动强度是个性化的,使用心率和VO2max,每日百分比变化.
主要成果:
- 在WPG中,体力活动 (52.5%) 和VO2max (16.1%) 显著增加.
- 体重 (-10.2%),脂肪质量 (-17.2%),腹部脂肪 (-4.8%),缩血压 (-9.6%) 和血糖 (-16.9%) 显著减少.
- 在WPG中,显著改善了脂质谱和肝酶 (AST,ALT),总蛋白质,白蛋白,胆红素和肝超声波得分.
结论:
- 12周的步行干预,结合一致的饮食,有效地改善了老年人的身体组成和心脏代谢因素.
- 该干预导致肝功能标志物和代谢综合征和MASLD患者的成像结果显著改善.
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