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Updated: May 10, 2025

Author Spotlight: Enhanced Murine AAA Model Using Elastase to Mimic Human Aneurysms
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揭示内动脉瘤和腹腔大动脉瘤之间共享的分子和机械特征:全面的基因组分析

Xiao Liu1,2, Zhenjun Li3, Hongzhen Xu4

  • 1Department of Neurosurgery, The Engineering Technology Research Center of Education Ministry of China, Guangdong Provincial Key Laboratory On Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Zhujiang Hospital, Southern Medical University, The National Key Clinical Specialty, Guangzhou, 510282, China.

Orphanet journal of rare diseases
|April 24, 2025
PubMed
概括

这项研究发现,内和腹部大动脉动脉瘤中存在共同的分子机制. 基因ITGA11可能是这些相关血管疾病的关键生物标志物.

关键词:
腹腔大动脉动脉瘤是什么在ITGA11中,我们可以看到:与免疫相关的与免疫相关的内动脉瘤 内动脉瘤

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Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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