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针对局部前列腺癌进行ADT的男性的性活动:叙事文献综述
Laeticia Creidy1,2, Daniel Taussky1, Frederic Pouliot2
1Department of Radiation Oncology, Montreal University Hospital Centre, Montréal H2X 0C1, Canada.
Asian journal of andrology
|April 25, 2025
概括
雌激素剥夺疗法 (ADT) 影响性功能,但在治疗期间,约有10分之一的男性保持性活跃. 在ADT之前活跃的男性中,这一比例更高,这凸显了解决性健康问题的重要性.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 性医学性医学性医学性医学
背景情况:
- 抗雄激素剥夺疗法 (ADT) 是晚期前列腺癌的基石治疗.
- ADT通常会导致显著的副作用,包括对性功能的负面影响.
- 保持性活动是许多患者生活质量的关键方面.
研究的目的:
- 确定在雄激素剥夺疗法 (ADT) 期间和之后保持性活跃的男性比例.
- 分析ADT对大量患者队列中的性活动率的影响.
- 为临床考虑提供基于证据的关于ADT期间性功能的见解.
主要方法:
- 对过去20年发表的随机临床试验进行了全面的文献综述.
- 选择了在基线,在ADT期间和之后报告性功能数据的研究.
- 使用患者报告的结果指标评估性功能,包括性强度和性活动评估.
主要成果:
- 分析了2947名患者 (平均年龄70岁) 的数据.
- 在基线时,49.9%的患者报告性活动.
- 在6个月,12个月和2年ADT后,中位数的性活动率分别为10.3%,8.9%和8.3%.
结论:
- 大约十分之一的男性在接受ADT时保持性活动.
- 接受ADT的性活跃男性的比例可能在治疗前性活跃的男性中更高.
- 在接受ADT的男性的管理中,应该考虑和解决性活动.
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