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在外部光束放射治疗剂量监测中,考虑TLD对CBCT协议的反应

Andrew J White¹, Cliff G Hammer¹, Matthew W Brenner²

¹Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Journal of applied clinical medical physics

|April 25, 2025

概括

LiF热发光剂量计 (TLD) 对千伏 (kV) 圆束CT (CBCT) 成像显示了可变的响应. 量化这种TLD对CBCT的反应可以确保在放射治疗中精确的剂量验证,特别是在复杂的病例中.

科学领域:

医学物理医学物理
辐射瘤学辐射瘤学

背景情况:

在放射治疗中,LiF热发光剂量计 (TLD) 对于剂量验证至关重要.
TLD 呈现出能量依赖的反应,特别是在成像中使用的千伏 (kV) X射线束,而不是巨电压 (MV) 处理束.
此前已经报告过TLD对kV光束的过度响应,当校准到MV光束时.

研究的目的:

量化 LiF TLD 对各种束计算断层扫描 (CBCT) 协议的响应.
评估MV校准对CBCT成像期间TLD响应的影响.
提高复杂治疗场景和心血管植入式电子设备 (CIED) 患者的剂量验证准确度.

主要方法:

调查了三个Varian OBI和三个Elekta XVI CBCT协议.
定位的TLDs在一个组织等价的幻影在不同距离的场中心.
将TLD校准为6MV光子束,以根据CBCT协议确定它们的响应.

主要成果:

在场内最大的TLD响应在0.82至4.80cGy (Varian OBI) 和0.06至2.69cGy (Elekta XVI) 之间.
场外CBCT响应从场边呈指数级下降.
不确定性通常低于3%,但场边 (6%) 和远距离位置 (34%) 是例外.

结论:

用MV校准测量CBCT协议的测量TLD反应允许隔离治疗剂量.
通过将测量的治疗剂量与治疗计划系统 (TPS) 的预测进行比较,可以提高准确剂量验证.
CBCT反应可以改变报告的治疗剂量高达2.5%.

关键词:

在CBCT中,CBCT是CBCT.区分区分区分区分区分区分区分区分顶级域名 (TLD) 是一个TLD.剂量验证剂量验证在体内进行体内剂量计.

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