在积极的精神分裂症和月经周期调节效应中的非典型语言横向化
Helene Hjelmervik1, Josef J Bless2, Julien Laloyaux3
1School of Health Sciences, Kristiania University College, Bergen, Norway.
Comprehensive psychoneuroendocrinology
|April 25, 2025
概括
整个月经周期的荷尔蒙波动会影响不同精神分裂特征的女性的语言侧面化. 较高的精神分裂症在高雌激醇阶段显示出右半球使用率更高,而不是低精神分裂症.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 精神病学是一个精神病学.
背景情况:
- 以前的研究表明,高精神分裂型的男性具有非典型的语言不对称性,但女性的研究结果不一致.
- 语言侧面化的性别差异可能涉及性激素,因为半球不对称性随着月经周期的波动而波动.
研究的目的:
- 调查高与低阳性精神分裂型女性群体中的语言横向化.
- 检查月经周期 (卵泡与月经期) 对语言横向化的影响.
- 复制有关月经周期对注意力条件的影响的发现.
主要方法:
- 用一个辅音-母音二语听力测试来评估语言侧面化.
- 39名女性参与者在月经 (低 Estradiol) 或卵泡 (高 Estradiol) 阶段进行了测试.
- 注意力被调节为调查半球处理.
主要成果:
- 毛囊阶段的参与者表现出增强的认知控制,在左侧注意力下表现更好.
- 在非强迫条件下,高阳性精神分裂型个体在卵泡阶段与月经阶段相比,右半球参与度增加.
- 低阳性精神分裂型个体在卵泡阶段表现出左半球主导度的增加.
结论:
- 高精神分裂型的语言侧面化是灵活的,受到荷尔蒙变化的影响,特别是雌激素.
- 淋巴腺激素可能调节半球间抑制,导致分裂型组之间的侧向化差异.
- 雌激醇可能具有神经保护作用,这可能解释了观察到的荷尔蒙对精神分裂症语言处理的影响.
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