隔离右心室辅助装置作为原发性右心力衰竭的持久支持的结果:INTERMACS分析
Edo Y Birati1,2, E Wilson Grandin3, Robert S Zhang4
1Division of Cardiology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
JHLT open
|April 25, 2025
概括
现在对隔离右心室辅助器件 (iRVAD) 的结果有了更好的理解. 虽然iRVAD的存活率低于左心室辅助装置 (LVAD),但对于孤立的右侧心力衰竭患者来说是可行的.
科学领域:
- 心脏病学 心脏病学
- 机械循环支持 机械循环支持
- 心脏外科手术 心脏外科手术
背景情况:
- 使用用于左心室辅助器件 (LVAD) 设计的与隔离右心室辅助器件 (iRVAD) 的结果没有得到充分记录.
- 右心室衰竭通常需要机械循环支持.
研究的目的:
- 将接受iRVAD的患者的临床特征和结果与接受LVAD和双心室辅助器件 (BiVAD) 的患者进行比较.
- 评估iRVAD在孤立右侧心力衰竭患者的可行性和生存率.
主要方法:
- 来自机械辅助循环支持 (INTERMACS) 机构间注册表 (2006-2017) 的患者的回顾性分析.
- 将iRVAD结果与LVAD和BiVAD患者队列进行比较.
- 评估的主要结局是2年生存率.
主要成果:
- 共有26名患者接受了iRVAD (20,789名患者中的0.13%),其中有17名脉动流和9名连续流器.
- 大多数iRVAD患者是INTERMACS型号1 (46%) 患者,需要大量支持,包括体外膜氧化 (19%) 和机械通风 (50%).
- iRVAD (41.3%) 的两年生存率与BiVAD (45.2%) 类似,但明显低于LVAD (69.0%).
结论:
- 对于患有孤立右侧心力衰竭的患者,长期支持iRVAD是可行的.
- 对于特定的患者群体来说,iRVAD提供了一个潜在的机械循环支持选择.
- 进一步的研究可能会优化iRVAD的使用并改善右心室衰竭的结果.
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