消除Helicobacter pylori对代谢参数和身体组成 (包括骨肌肉质量) 的影响:一项匹配的病例对照研究
Suh Eun Bae1, Kee Don Choi2, Jaewon Choe1
1Division of Gastroenterology, Health Screening and Promotion Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Gut and liver
|April 25, 2025
概括
杆菌根除改善了45岁以上患者的代谢健康,降低了血压和炎症. 然而,像BMI和肌肉质量这样的身体组成总体上保持不变.
科学领域:
- 胃肠病学 胃肠病学
- 代谢健康 代谢健康
- 身体组成分析 身体成分分析
背景情况:
- 关于 Helicobacter pylori 根除对代谢参数的影响存在不一致的发现.
- 这项研究调查了H. pylori根除对代谢健康和身体组成的影响.
研究的目的:
- 评估H. pylori根除对代谢参数的影响.
- 评估身体组成的变化,包括脂肪和骨肌肉质量,H. pylori根除后.
主要方法:
- 对接受健康查的无症状患者的回顾性分析.
- 823名H. pylori根除患者和823名非根除患者之间的代谢参数和身体组成的比较.
主要成果:
- 根除H. pylori显著降低了血压,红细胞沉积率和糖化血红蛋白.
- 总体而言,BMI,体脂质量或骨肌肉质量没有显著变化.
- 在45岁以上的患者中,根除降低了血压,炎症和改善了脂质概况,根除组的BMI更高.
结论:
- 根除H. pylori对代谢参数有好处,特别是在老年人 (>45岁) 中.
- 显著的改善包括降低血压,血糖水平,炎症和更好的脂质概况在>45小组.
- 身体组成指标,如BMI,体脂肪和骨肌肉质量,在各组之间没有显著差异.
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