新诊断的自身免疫性胃炎的发病率和演变在一个大型的西班牙回顾性队列中
Esteban Fuentes-Valenzuela1, Sergio Escribano Cruz2, Javier Parra Villanueva3
1Gastroenterology , Hospital Universitario Infanta Elena , España.
Revista espanola de enfermedades digestivas
|April 25, 2025
概括
自身免疫性胃炎 (AIG) 影响1.6%的接受胃镜检查的患者. 有阳性表皮细胞抗体的人中,有一半的患者表现出显著的缩,表明疾病进展.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
- 在瘤学瘤学.
背景情况:
- 自身免疫性胃炎 (AIG) 正因其流行率和疾病进展而受到越来越多的关注.
- 了解AIG的自然历史对于患者管理至关重要.
研究的目的:
- 确定具有阳性表皮细胞抗体的患者中AIG的患病率.
- 为了分析AIG随着时间的推移的组织学进展.
主要方法:
- 对接受胃镜检查 (2013-2023) 的阴顶细胞抗体阳性患者进行了回顾性观察性研究.
- 基于缩和发育不良的组织学分期 (0-III).
- 随访内镜数据分析疾病进展.
主要成果:
- 在26,798次内镜检查中,AIG患病率为1.6%.
- 在基线时,50.5%患有缩性胃炎 (第二阶段),1.6%患有第三阶段 (发育不良/癌症).
- 随访显示,高级阶段的病例显著增加,潜在的AIG病例减少.
结论:
- AIG 患病率低,但进展显著.
- 有阳性表皮细胞抗体的半数患者出现显著缩,突出显示需要监测.
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