在重症监护室的侵入性角膜炎:我们现在在哪里?
Jose A Vazquez1, Lissette Whitaker1, Ana Zubovskaia1
1Division of Infectious Disease, Medical College of Georgia, Augusta University, 1120 15th Street, Augusta, GA 30912, USA.
Journal of fungi (Basel, Switzerland)
|April 25, 2025
概括
由非白虫Candida物种引起的侵入性真菌感染在ICU中正在增加. 抗真菌耐药性增加使治疗复杂化,强调需要及时诊断和管理,以减少患者的死亡率.
科学领域:
- 临界护理医学 临界护理医学
- 传染性疾病 传染性疾病
- 菌类学 菌类学是指菌类学.
背景情况:
- 侵入性真菌感染,主要是角膜炎,在重症监护室 (ICU) 很常见.
- 虽然*Candida albicans*在历史上占主导地位,但非*albicans Candida*物种越来越多地参与其中.
- 这些物种中抗真菌耐药性的增加构成了重大的临床挑战.
研究的目的:
- 审查目前的流行病学趋势,在ICU的入侵性角膜炎.
- 讨论与侵袭性 кандидоз相关的诊断挑战.
- 概述在重症患者中侵袭性角膜病的当代管理策略.
主要方法:
- 关于ICU环境中的侵袭性候群病的当前文献的综述.
- 对流行病学趋势的分析,重点关注 *Candida* 种类的分布.
- 对诊断方法和抗真菌治疗指南的评估.
主要成果:
- 侵袭性感染的发病率越来越高,这些感染是由非白虫Candida*物种 (*C. glabrata*, *C. parapsilosis*) 引起的.
- 在*Candida*物种中观察到日益增长的抗真菌耐药性,使治疗选择复杂化.
- 非特定的临床表现和诊断延迟有助于增加发病率和死亡率.
结论:
- 在ICU中对侵袭性候群病的诊断和管理仍然具有挑战性.
- 及时识别和适当的抗真菌治疗对于改善结果至关重要.
- 重症监护医生必须保持对侵袭性候群病的高度怀疑指数.
相关概念视频
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
3.9K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
3.9K
01:22Healthcare Associated Infections II: Preventive Measures
2.3K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.3K
01:20Infection
6.5K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
6.5K