克里索斯波里亚菌种Chrysosporium的特征 病原体导致马的皮肤菌根
Yelena Kukhar1, Gulshat Bailina1, Ainura Smagulova1,2,3
1Research Platform of Agricultural Biotechnology, S. Seifullin Kazakh Agrotechnical Research University, Astana 010011, Kazakhstan.
Journal of fungi (Basel, Switzerland)
|April 25, 2025
概括
新的致病性Chrysosporium菌株正在哈萨克斯坦引起马类皮肤菌株. 这些真菌感染呈现出多种病变和不同的抗真菌敏感性,影响该地区的马健康.
科学领域:
- 兽医真菌学 兽医真菌学
- 马类皮肤病学 马类皮肤病学
- 发现病原体发现
背景情况:
- 马皮菌在哈萨克斯坦普遍存在,与畜牧业和马术活动有关.
- 类真菌,如克里索斯波里亚种类,是新兴的病原体,导致马的皮肤植物病.
- 这些真菌会降解质素,并具有耐热性,这有助于它们的致病性.
研究的目的:
- 调查哈萨克斯坦马匹皮肤病变中Chrisosporium菌株的生物特性和病原性.
- 为了识别和表征新兴的菌病原体,负责马类皮肤植物病.
- 评估分离的Chrysosporium菌株的临床表现和抗真菌敏感性.
主要方法:
- 从马类皮肤病变中分离和培养真菌菌株.
- 隔离物体的形态和文化特征.
- 使用核糖体基因测序进行遗传鉴定.
- 评估酸和酸溶解活性.
- 对抗真菌药物耐药性的评估.
主要成果:
- 他们分离了两种Chrysosporium菌株,分别被称为Chrysosporium kreiselii和Chrysosporium zonatum.
- 克里塞利菌会引起经典皮肤菌病变,表现出型/溶性质,并且具有抗真菌耐药性.
- C. zonatum诱导非典型的病变 (,斑疹),对抗真菌更敏感,并表现出皮性质.
- 两种菌株都显示出98.9%的遗传特征与已知的克里索斯波序列相同.
结论:
- 在哈萨克斯坦出现了新的致病性Chrysosporium菌株 (C. kreiselii和C. zonatum),导致马的皮肤病理.
- 在两种已识别的菌株之间观察到不同的临床表现和致病行为.
- 需要对新发现的马类真菌病原体进行全面的回顾性分析和病原性表征.
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