封装技术以提高阿斯塔丁作为功能性料成分的利用率
Matteo Vitale1,2, Joaquin Gomez-Estaca3, Janete Chung2
1Department of Chemistry, Bioscience, and Environmental Engineering, University of Stavanger, 4021 Stavanger, Norway.
Marine drugs
|April 25, 2025
概括
喷雾干燥和脂质体等封装技术显著提高了素 (AX) 在鱼料中的稳定性和生物可用性. 这提高了细胞活力,并减少了彩虹鱼细胞中的氧化应激.
科学领域:
- 水产养殖营养水产养殖营养
- 生物技术是生物技术.
- 食品科学 食品科学 食品科学
背景情况:
- 素 (AX) 是一种具有抗氧化特性的有价值的胡卜素,但其作为功能性料成分的应用受到稳定性和生物可用性差的限制.
- 封装技术提供了一种有希望的方法来克服这些局限性并提高AX的有效性.
研究的目的:
- 评估喷雾干燥和脂质体捕获在增强天然和合成来源的阿斯丁 (AX) 稳定性和生物可用性的有效性.
- 用彩虹鱼细胞系来评估封装AX配方的物理化学特性,热稳定性和体外性能.
主要方法:
- 天然和合成的阿斯塔山丁 (AX) 用喷雾干燥和脂质体捕获进行了封装.
- 封装AX配方的特点是封装效率,物理化学性质和热稳定性.
- 实验室内研究使用RTL-W1细胞进行,以评估细胞活力和反应性氧物种 (ROS) 生产.
主要成果:
- 喷雾干燥和脂质体捕获都实现了高封装效率 (73-89%) 和AX的优良热保护.
- 封装的AX在80°C保持稳定2小时,在100°C保持稳定30分钟.
- 在体外试验表明,在用封装的AX.治疗的RTL-W1细胞中,细胞活力得到改善,ROS产量减少.
结论:
- 封装显著提高了阿斯塔山丁 (AX) 的稳定性和生物可用性,使其成为鱼类料中更有效的功能成分.
- 喷雾干燥和脂质体捕获是优化水产养殖中AX利用的可行方法.
- 进一步的研究可以利用这些发现来开发改进的鱼配方,增强营养和健康益处.
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