SMC4通过Rheb/mTOR通路促进前列腺癌细胞的扩散和转移

Wei Zhang1,2, Siyuan Qin3, Xiaokang Li4

  • 1School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, 518053, China.

概括

染色体蛋白4 (SMC4) 的结构维护通过增强糖解和与GLUT1.1相互作用,促进前列腺癌转移. 抑制SMC4可以通过Rheb/mTOR途径减少癌细胞的增殖,迁移和转移.

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