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Updated: May 10, 2025

Assessment of the Effects of Endocrine Disrupting Compounds on the Development of Vertebrate Neural Network Function Using Multi-electrode Arrays
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受到PBDE暴露影响的神经递质系统:体外和体外神经毒性研究的见解

Wendy Argelia García-Suastegui1, Cynthia Navarro-Mabarak2, Daniela Silva-Adaya3,4

  • 1Departamento de Biología y Toxicología de la Reproducción, Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla, Puebla C.P. 72570, Mexico.

Toxics
|April 25, 2025
PubMed
概括

聚化二乙烯 (PBDE),持久性阻燃剂,破坏神经递质通路,导致神经毒性. 环境监测对于降低人类和生物群暴露风险至关重要.

关键词:
神经毒性的作用.这些神经递质是神经递质.聚化二乙烯乙烯的多化二乙烯.

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Drugs affecting neurotransmitter synthesis can impact the adrenergic neuron and the synthesis of neurotransmitters. For example, α-methyltyrosine and carbidopa target specific enzymes involved in catecholamine synthesis. α-methyltyrosine inhibits the enzyme tyrosine hydroxylase, which converts tyrosine into dopamine. By blocking this enzyme, α-methyltyrosine reduces dopamine production and other catecholamines. Carbidopa, on the other hand, inhibits the enzyme dopa decarboxylase,...
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