辐射诱导癌症风险模型之间的可变性,用于估计重症监护病房患者的癌症风险
Emilio Quaia1, Chiara Zanon1, Riccardo Torchio2
1Department of Radiology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.
概括
对ICU患者的瘤风险估计在不同的辐射风险模型中差异很大. 然而,在这些模型之间的风险值的一致性方面,发现了良好的或优秀的协议.
科学领域:
- 医学物理 医学物理
- 放射学 放射学是指放射学
- 辐射瘤学 辐射瘤学
背景情况:
- 重症监护室 (ICU) 的患者经常使用电离辐射进行频繁的诊断成像.
- 估计与这种辐射暴露相关的瘤风险对于患者安全至关重要.
- 不同模型间风险估计的变化需要仔细评估.
研究的目的:
- 评估ICU患者因诊断辐射暴露而导致的瘤风险的变化.
- 使用BEIR VII,ICRP 103和美国EPA风险模型进行风险估计的比较.
- 评估风险预测在这些既定模型中的一致性.
主要方法:
- 71名接受X射线检查的ICU患者的回顾性观察性研究.
- 在入院期间,计算每位患者累计有效辐射剂量.
- 使用BEIR VII,ICRP 103和美国EPA模型估计终身可归因风险 (LAR).
- 使用弗里德曼测试和类内相关系数 (ICC) 的统计分析.
主要成果:
- 在评估模型之间观察到器官,白血病和所有癌症风险值的显著差异.
- 与美国EPA和BEIR VII相比,ICRP 103模型始终估计所有癌症和白血病的风险较低.
- 尽管存在数值差异,但ICC表示在模型中的风险一致性方面达成良好至优异的协议 (>0.75至>0.9).
结论:
- 来自不同模型的癌症风险值显示了显著的数值差异.
- 模型之间的风险估计的一致性是强大的,与良好的到优秀的协议.
- 这些发现强调了理解模型特定输出的重要性,同时认识到ICU患者风险评估的整体一致性.
关键词:
贝尔第七集 贝尔第七集计算机断层扫描 (CT) 是一种计算机断层扫描.有效剂量的有效剂量.重症监护病房的重症监护病房是一个重症监护病房.致癌性风险 致癌性风险 致癌性风险暴露于辐射的辐射暴露.更多相关视频
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