Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Bioremediation00:46

Bioremediation

18.1K
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
18.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Phenolic Acids and Their Derivatives in Tea: Chemical Diversity, Processing Changes, Sensory Contributions, and Health Implications-A Comprehensive Review.

Comprehensive reviews in food science and food safety·2026
Same author

Comparative Phenolic Composition, Antioxidant, Antimalarial, and Erythroprotective Activities of Leaves, Flowers, and Fruits of Ora-pro-nobis (Pereskia aculeata).

Chemistry & biodiversity·2026
Same author

Toward human-relevant toxicology: a decision-oriented roadmap integrating modern tools for the safety evaluation of novel foods, functional ingredients, and nutraceuticals.

Critical reviews in food science and nutrition·2026
Same author

How the "high in sodium" warning and information about emerging technologies on burger labels influence consumer purchase decisions.

Meat science·2026
Same author

Phenolic Compounds from Araticum Pulp (<i>Annona crassiflora</i> Mart.) Modulate Inflammatory Targets: Insights from <i>in Vitro</i> and <i>in Silico</i> Approaches.

ACS omega·2026
Same author

Polyphenols from Pliniajaboticaba peels: cellular antioxidant activity, anti-obesity effects, microencapsulation, controlled release, and functional beverage development.

Food research international (Ottawa, Ont.)·2026

相关实验视频

Updated: May 10, 2025

Extraction and Analysis of Taiwanese Green Propolis
06:50

Extraction and Analysis of Taiwanese Green Propolis

Published on: January 7, 2019

8.4K

装有巴西绿色的酸盐基微囊减少反应性氧物种的产生,减少炎症性细胞因子,并减轻肠道炎症.

Marcelo Franchin1, Ana Sofia Martelli Chaib Saliba2, Anderson Dos Santos Ramos3

  • 1Bioactivity and Applications Laboratory, Department of Biological Sciences, Faculty of Science and Engineering, University of Limerick, Limerick, Ireland; Graduate Program in Biological Sciences, Federal University of Alfenas (Unifal-MG), Alfenas, Brazil.

International journal of biological macromolecules
|April 25, 2025
PubMed
概括

装有巴西绿色提取物 (EEGP-MC) 的酸盐微囊有效降低炎症,并在实验性结肠炎中保护结肠. 这种创新的输送系统在治疗炎症方面表现有前途.

关键词:
阿尔金酸盐是一种酸盐.抗氧化剂是一种抗氧化剂.细胞因子 (cytokines) 是一种细胞因子.梅罗内拉画廊 (Galleria mellonella) 是一个著名的画廊.炎症 炎症是一种炎症.巨细胞是一个巨细胞.微囊中的微囊蜂是一种天然的植物.

更多相关视频

Generation of Alginate Microspheres for Biomedical Applications
10:33

Generation of Alginate Microspheres for Biomedical Applications

Published on: August 12, 2012

20.6K
Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs
07:33

Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs

Published on: July 6, 2015

11.3K

相关实验视频

Last Updated: May 10, 2025

Extraction and Analysis of Taiwanese Green Propolis
06:50

Extraction and Analysis of Taiwanese Green Propolis

Published on: January 7, 2019

8.4K
Generation of Alginate Microspheres for Biomedical Applications
10:33

Generation of Alginate Microspheres for Biomedical Applications

Published on: August 12, 2012

20.6K
Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs
07:33

Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs

Published on: July 6, 2015

11.3K

科学领域:

  • 生物材料科学 生物材料科学
  • 药理学 药理学是指药理学的学科.
  • 胃肠病学 胃肠病学

背景情况:

  • 性结肠炎的特征是肠道炎症,目前的治疗方法在有效性和安全性方面面临限制.
  • 巴西绿色石具有抗炎性质,具有治疗炎症状况的潜力.
  • 控制释放技术可以提高生物活性化合物的输送和有效性.

研究的目的:

  • 开发基于酸盐的微囊,装有绿色的乙醇提取物 (EEGP-MC).
  • 评估EEGP-MC对细胞因子,活性氧物种 (ROS) 和实验性结肠炎的抗炎作用.
  • 评估EEGP-MC在慢性炎症管理中的安全性和治疗潜力.

主要方法:

  • 制造酸盐微囊,封装绿色 (EEGP) 的乙醇提取物.
  • 从微囊中释放类化合物和Artepillin C的体外研究.
  • 评估EEGP-MC对THP-1细胞培养中的TNF-α,IL-6和ROS产生的影响.
  • 在实验性结肠炎模型中对EEGP-MC进行体内评估,评估结肠病变和炎症标志物.

主要成果:

  • EEGP-MC在肠道阶段显示了化合物和Artepillin C的受控释放.
  • EEGP-MC预处理显著降低了细胞培养中的TNF-α,IL-6水平和ROS产量.
  • 在实验性结肠炎中,口服EEGP-MC明显减少了结肠病变 (86.1%),而单独使用EEGP则 (54.9%).
  • 在肠道组织中,EEGP-MC治疗抑制了关键的炎症性细胞因子 (TNF-α,IL-6,IL-1β).

结论:

  • EEGP-MC代表了巴西绿色的有效的控制释放系统.
  • 在实验性结肠炎中,EEGP-MC表现出显著的抗炎和保护作用.
  • 这项技术有望在食品和制药行业应用,用于治疗慢性炎症.