从果中制备的3型耐药粉通过肠道微生物群调节缓解了超脂血症
Yutong Zhang1, Jingyi Liu2, Xiaoai Chen2
1Spice and Beverage Research Institute, Chinese Academy of Tropical Agricultural Sciences, National Center of Important Tropical Crops Engineering and Technology Research, Key Laboratory of Processing Suitability and Quality Control of the Special Tropical Crops of Hainan Province, Wanning 571533, Hainan, China; Chinese Academy of Tropical Agricultural Sciences, Haikou 570105, Hainan, China; Sanya Research Institute, Chinese Academy of Tropical Agriculture Sciences, National Key Laboratory for Tropical Crop Breeding, Sanya 572025, Hainan, China; College of Food Science, Northeast Agricultural University, Harbin 150030, China.
加热的杰克果耐性粉 (JFRS3) 通过改善肠道微生物群和仓鼠的血液脂质概况,有效地管理超脂血症. 这种经热处理的耐热粉在高脂肪饮食引起的健康问题上显示出比原始耐热粉更优越的益处.
科学领域:
- 营养科学 营养科学
- 微生物学 微生物学
- 生物化学 生物化学
背景情况:
- 来自原始来源的耐药粉 (RS) 影响肠道微生物群和超脂血症.
- 人类饮食中常见的加热食品中的RS对高脂血症的作用尚不清楚.
- 从热处理的麻果本土粉 (JFRS3) 中研究RS对于了解其影响至关重要.
研究的目的:
- 为了评估JFRS3对含肠道微生物的金色仓鼠的抗高脂效应.
- 为了比较JFRS3与原始耐性粉 (JFNS) 的疗效.
- 探索JFRS3的结构性质,肠道微生物群调节和超脂血调节之间的联系.
主要方法:
- 描述JFRS3的结构性质 (形态,结晶性,晶体结构).
- 用JFRS3和JFNS给高脂肪饮食中的金色仓鼠.
- 分析血液脂质概况 (HDLC,TG,TC,LDL-C),肝脏健康状况和肠道微生物组成.
主要成果:
- JFRS3 呈现出明显的块状形状,有序结构和C型结晶性.
- JFRS3显著改善了脂质概况,增加了HDLC,减少了TG,TC和LDL-C.
- 与JFNS相比,JFRS3调节了肠道微生物群,增强了多样性和特定的微生物种群,导致体重增加减少和脂质资料改善.
结论:
- 通过调节肠道微生物群和改善脂质配置文件,JFRS3显示出显著的抗高脂效应.
- JFRS3的结构特征与其有益的健康影响有关.
- JFRS3提出了一个有希望的替代策略,用于管理高脂肪饮食引起的高脂血症.
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