在缺血性中风后的功能独立性与中风前体力活动的关联中没有性别差异
Shuangfang Fang1,2,3, Baixiang Zhang4, Hanhan Lei1,2,3
1Department of Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Gulou District, Fuzhou, 350001, China.
Scientific reports
|April 25, 2025
概括
脑卒中前的身体活动与缺血性脑卒中后更好的功能独立性有关. 这种关联在男性和女性中都被观察到,这表明体育活动有益于中风恢复,而不论性别.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 公共卫生 公共卫生
背景情况:
- 脑卒中前的身体活动与脑卒中后的功能结果之间的关系尚未得到充分证实.
- 了解这种关联对于制定有效的中风预防和康复策略至关重要.
- 研究这种关系中的潜在的基于性别的差异对于个性化医学来说很重要.
研究的目的:
- 探索急性缺血性中风患者中中风前的身体活动水平与功能结果之间的关联.
- 为了确定这种关联是否在男性和女性之间有所不同.
主要方法:
- 采用了前性队列研究设计.
- 在中风前的体力活动被用Saltin-Grimby体力活动水平尺度 (SGPALS) 评估.
- 功能独立被定义为在中风后三个月的0-2的修改的兰金尺度 (mRS) 评分.
- 用多变量调整后勤回归模型来估计赔率比率.
主要成果:
- 身体活跃的参与者在中风后三个月实现功能独立的几率明显更高 (经调整的OR 4.14).
- 这一关联在按性别分层时仍然显著,男性 (调整后OR为4.75) 和女性 (调整后OR为3.64) 均显示出更好的几率.
- 在中风前的身体活动与功能独立之间的关联中,没有观察到明显的性别差异.
结论:
- 脑中风前的体力活动与缺血性脑中风后三个月的功能独立性有关.
- 在中风前的身体活动对中风恢复的好处似乎在两性之间一致.
- 在中风前促进身体活动可能会改善恢复和功能结果.
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