根据生活方式风险得分轨迹的癌症风险:基于人口的队列研究
Thi Minh Thu Khong1, Thi Tra Bui1, Hee-Yeon Kang1
1National Cancer Center Graduate School of Cancer Science and Policy, Goyang, Republic of Korea.
BJC reports
|April 25, 2025
概括
追踪不健康的生活方式得分轨迹对于预防癌症至关重要. 高风险轨迹显著增加患各种癌症的风险,强调健康习惯的重要性.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 个人生活方式行为与癌症风险有关,但它们的综合影响尚未得到充分理解.
- 这项研究调查了生活方式风险因素对韩国癌症发病率的影响.
研究的目的:
- 分析生活方式风险得分轨迹与癌症风险之间的关联.
- 识别不健康行为模式及其对癌症发展的影响.
主要方法:
- 从健康检查数据 (2002-2003) 中利用了3,451,189名韩国成年人的大量队列.
- 基于组的轨迹建模评估了生活方式风险得分 (吸烟,酒精,体重,不活动) 从2002年至2007年.
- 考克斯的比例危险模型检查了2008-2019年的癌症发病率.
主要成果:
- 根据生活方式风险分数,确定了男性的7个轨迹和女性的4个轨迹.
- 高风险的生活方式轨迹与大多数癌症的风险增加相关,包括肺癌,肝癌和结直肠癌.
- 在高风险的男性中,前列腺癌风险与前列腺癌风险有相反的关联.
结论:
- 采用和保持健康的生活方式行为对于有效的癌症预防至关重要.
- 减少不健康的综合行为可以减轻不同人群的癌症风险.
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