在多药耐药结核病的老年患者中,治疗级联的消耗
1Department of Epidemiology, School of Public Health, Fudan University, Shanghai, People's Republic of China;, Key Laboratory of Health Technology Assessment, National Health Commission of the PRC, Fudan University, Shanghai, People's Republic of China.
概括
患有多种药物/利番素耐药结核病 (MDR/RR-TB) 的老年患者经历了更高的治疗消耗. 针对性干预对于改善这种脆弱人群的治疗开始和坚持治疗至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 老年学是一门学科.
背景情况:
- 患有多种药物/利番素耐药结核病 (MDR/RR-TB) 的老年患者在获得成功治疗结果方面面临重大挑战.
- 识别MDR/RR-TB治疗级联中的与年龄相关的差异和消耗点对于改善护理至关重要.
研究的目的:
- 为了确定MDR/RR-TB治疗级联中的差距和年龄差异.
- 确定导致中国江省老年MDR/RR-TB患者消耗的因素.
主要方法:
- 一项为期7年的回顾性队列研究 (2015-2021) 分析了被诊断为MDR/RR-TB的患者.
- 该研究评估了治疗级联:诊断确认,治疗开始,持续6个月和治疗成功.
- 在布的连续步骤之间评估了磨损.
主要成果:
- 老年患者 (≥60岁) 在治疗开始 (22.5%),持续6个月 (12.8%) 和整体治疗成功 (31.7% vs. 15.6%在年轻患者中) 中显示出显著更高的消耗率.
- 尽管消耗率很高,但老年患者的整体消耗率从长度上从77.9%降至35.5%.
- 与不启动相关的因素包括年龄较大,常规药物敏感性测试和缺乏医疗保险;停药与旅行距离和缺乏调整方案有关.
结论:
- 对于中国的老年患者来说,MDR/RR-TB治疗级联中的磨损仍然是一个重要问题.
- 针对性干预以改善治疗开始和坚持为重点,对于这一群体来说至关重要.
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