跑步机跑步对临床健康犬体内循环皮质醇度的影响
Jennifer S Eiermann1, Laureen M Peters2, Bérénice Lutz2
1Division of Small Animal Internal Medicine, Department of Veterinary Medicine, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Animals : an open access journal from MDPI
|April 26, 2025
概括
在健康的狗中,跑步机运动不能可靠地刺激皮质醇的释放. 这表明它可能不是ACTH刺激测试的合适替代品来诊断低 adrenocorticism.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 内分泌学 在内分泌学.
- 狗的健康 狗的健康
背景情况:
- 基底皮质醇水平用于选慢性胃肠道问题的狗的低上皮质症 (HAD).
- 低基底皮质醇值经常导致不必要的ACTH刺激测试,增加成本和狗患者的压力.
研究的目的:
- 评估跑步机运动作为一种潜在的非侵入性方法来刺激狗的皮质醇释放.
- 为了确定短期跑步机运动是否可以可靠地提高皮质醇水平,用于诊断目的.
主要方法:
- 19只健康的物狗接受了基线血液采集以测量血清皮质醇.
- 然后,这些狗接受了10分钟的跑步机炼 (步行和慢跑),然后30分钟的休息时间.
- 第二个血液样本是在运动后 (T1) 采集的,并与基线 (T0) 进行比较,使用随机化 (变换) 测试对配对数据进行比较.
主要成果:
- 运动前血清皮质醇的中位数为1.36μg/dL (IQR:0.9-2.095),而运动后的水平为1.1μg/dL (IQR:0.895-1.585).
- 在运动前和运动后的皮质醇水平之间没有观察到统计学上显著的差异 (p = 0.0915).
- 运动后的皮质醇水平在19只狗中增加了9只,在19只狗中减少了10只.
结论:
- 跑步机上进行10分钟的运动,在活动后30分钟进行评估,似乎无法在健康的狗中可靠地刺激皮质醇的释放.
- 跑步机运动不太可能是ACTH刺激测试的可行的替代方案,用于诊断低皮质皮质.
- 在这项研究的健康狗队伍中,基础皮质醇度低于以前在文献中报告的水平.
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