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作为肝脏活检的替代品的非侵入性测试,用于评估MASLD

Julia Frączek¹, Aleksandra Sowa¹, Paulina Agopsowicz¹

¹Student Scientific Society at the Department of Internal, Autoimmune and Metabolic Diseases, School of Medicine, Medical University of Silesia, 40-055 Katowice, Poland.

Medicina (Kaunas, Lithuania)

|April 26, 2025

概括

与代谢功能障碍相关的脂肪性脂肪性肝病 (MASLD) 影响全球超过三分之一的成年人. 本综述探讨了非侵入性诊断方法,旨在减少对MASLD评估的侵入性肝活检的依赖.

科学领域:

肝病学和胃肠道学
代谢疾病代谢疾病
诊断的创新诊断的创新

背景情况:

与代谢功能障碍相关的脂肪性脂肪性肝病 (MASLD) 是一个普遍的全球健康问题,影响超过33%的成年人.
MASLD是肝脏相关发病率和死亡率的重要因素,也是慢性肝脏疾病的前体.
这是一种全身性疾病,与心血管疾病,慢性病,2型糖尿病和某些癌症的风险增加有关.

研究的目的:

审查目前和新兴的MASLD的非侵入性诊断方法.
评估这些非侵入性技术在临床实践中替代肝活检的潜力.
提供与未来MASLD.诊断和管理相关的数据.

主要方法:

对MASLD诊断现有文献的审查.
分析非侵入性诊断方法,包括血清学标记,多组学和像素成像技术,如肝脏弹性图像.
专注于具有临床应用潜力的方法.

主要成果:

肝脏活检仍然是黄金标准,但具有侵入性和风险.
非侵入性诊断方法,包括血清学标记,多组学和弹性图学,正在变得越来越重要.
新兴的非侵入性技术对准确的MASLD评估具有前景.

结论:

非侵入性诊断方法为MASLD提供了一种不那么侵入性的肝脏活检替代方案.
这些方法有可能在常规临床诊断中逐渐取代活检.
非侵入性诊断的进步对于管理日益增长的MASLD负担至关重要.

关键词:

在FIB-4中,FIB-4是第一个被指控的.马斯尔德马斯尔德是什么意思肝脏活检活检肝脏活检肝脏疾病是一种肝脏疾病.肝脏弹性图谱肝脏弹性图谱

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