系统性红斑狼在老年患者中的特征:基于病例的审查
Alexandr Ceasovschih1,2, Raluca-Elena Alexa1,2, Victorița Șorodoc1,2
1Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
Journal of clinical medicine
|April 26, 2025
概括
晚期发病的系统性红斑狼 (SLE) 在老年人中提出了独特的挑战. 这一案例凸显了SLE如何在老年人中表现异常,尽管有常见的症状,但需要仔细诊断.
科学领域:
- 类风湿病学 类风湿病学
- 内部医学 内部医学
- 老年病的医生 老年病的医生
背景情况:
- 系统性红斑狼 (SLE) 是一种复杂的自身免疫性疾病,通常影响年轻人.
- 晚期发病的SLE (诊断在老年人中) 提出了不同的临床和诊断挑战.
- 与年龄相关的免疫系统变化可能会影响老年人出现SLE.
研究的目的:
- 描述一个93岁患者晚期发病的系统性红斑狼病例.
- 突出老年人群中SLE的诊断困难和独特表现.
- 强调在出现非典型症状的老年患者中考虑SLE的重要性.
主要方法:
- 一个93岁的病人的病例报告显示,他有运动性呼吸不全,下肢胀和腹部疼痛.
- 排除的常见原因,包括心力衰竭,脏疾病,肝硬化,甲状腺功能低下和低蛋白血症.
- 诊断工作包括免疫测试,揭示高抗核抗体 (ANA),抗dsDNA抗体和低补充水平.
主要成果:
- 成功排除了患者的常见病因.
- 免疫学发现证实了活跃的系统性红斑狼 (SLE) 是患者症状的原因.
- 患者接受了皮质类固醇治疗,并被转诊进行类风湿学后续检查.
结论:
- 晚期发病的SLE在老年人中可以呈现出各种各样的,有时是非典型的症状.
- 在早期发病和晚期发病之间,SLE的临床表现可能会显著不同.
- 了解这些差异对于老年人群中SLE的准确诊断和管理至关重要.
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