认知康复作为一种可能的治疗方法在患有白发的患者
Francesco Marchet1,2, Daniele Belvisi1,2, Giorgio Leodori1,2
1Department of Human Neuroscience, Sapienza University of Rome, Viale dell'Università 30, 00185 Rome, RM, Italy.
Journal of clinical medicine
|April 26, 2025
概括
认知训练,包括阅读和写作,显著改善了白发作 (BSP) 患者的肉毒素 (BoNT) 治疗结果. 这种方法提供了一个有希望的,非侵入性的补充疗法,用于减少非自愿的和眼率.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 眼科医生 眼科 眼科
背景情况:
- 血发作 (BSP) 是一种焦点性 dystonia,导致非自愿的 orbicularis oculi 肌肉.
- 毒素 (BoNT) 是标准的治疗方法,但认知任务可能会调节症状.
- 研究认知训练作为BSP的BoNT的辅助.
研究的目的:
- 评估认知训练与BSP的BoNT结合的疗效.
- 评估阅读和写作任务对眼率和的影响.
- 为了确定认知训练是否提高BoNT治疗结果.
主要方法:
- 16名BSP患者被随机分为两组:认知训练+BoNT (A组,n=6) 和仅使用BoNT (B组,n=10).
- 认知训练包括三个月的结构化阅读和写作练习.
- rate (BR) 和 dystonic 是在基线,1个月和3个月测量的.
主要成果:
- 两组都显示了减少的BR,但A组的改善 (45.4%) 比B组 (12.6%) 大得多.
- 阅读和写作任务在减少BR和 dystonic方面非常有效 (p < 0.001).
- 在临床/人口统计特征和结果之间没有发现显著的相关性.
结论:
- 认知训练显著增强了BoNT对BSP患者眼率的治疗效果.
- 这表明认知训练是BSP的可行的非侵入性补充干预.
- 需要对更大的队列和神经生理学评估进行进一步的研究.
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